New iPhone Dev Agreement Bans the Use of Adobe's Flash-to-iPhone Compiler

Also tools/engines like Unity3D, MonoTouch, Titanium, Phonegap. Torque, Unreal.

In fact they pretty much banned anything that generates code.

If you’re programming in languages like Heskell, Gambit, Lua, Haxe, anything that’s not Apple controlled, you’re out of luck.

I’m sure there are a lot of startups rapidly hacking away developing for the iPad/iPhone right now that are feeling a giant middle finger from Mr Steve Jobs right now.